Yeah as @DoomedFPV suggested, as either its a bad connection to the ESC or that particular ESC is bricked :-(… but happy to hear you got your FC working at least!
If your ESC is actually working fine (except for the motor direction and you cant connect to blheli for whatever reason… you can also just swap any two of the ESC to motor wires and that will also reverse the motor spin direction. But best to figure out why its not connecting to BLheli configurator.