Calibrating Quattro ESC with Pixhawk

It does sound like you have not managed to complete the ESC calibration correctly.

It might be best to perform a manual ESC calibration by connecting the ESC’s directly to your R/C receiver using a using a ESC throttle hub. However since you have tried the one by one method it might be worth trying the motor 4 ESC again to check as maybe it did not save correctly.

Otherwise the last option is to get yourself a USB linker board so that you can connect your ESC to the PC and manually set the ESC calibration range for each one. It also allows you to check all the other ESC settings are the same between all 4 ESC’s